Description

2-Bromo-4-(4-Chlorophenyl)But-1-Ene is a versatile halogenated organic intermediate of significant importance in advanced chemical synthesis. Its unique structure, featuring both bromine and chlorine substituents on an alkenyl-phenyl backbone, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers with specific optical or electronic properties.
• Cross-Coupling Reactions: Acts as a competent electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in academic and contract research organizations (CROs).

Basic Information

Product Name	2-Bromo-4-(4-Chlorophenyl)But-1-Ene
CAS No.	731772-11-5
Molecular Formula	C10H10BrCl
Molecular Weight	245.54 g/mol
Synonyms	1-Butene, 2-bromo-4-(4-chlorophenyl)-; 2-Bromo-4-(4-chlorophenyl)-1-butene; 4-(4-Chlorophenyl)-2-bromobut-1-ene; (2-Bromo-4-(4-chlorophenyl)but-1-ene); 2-Bromo-4-(p-chlorophenyl)-1-butene; p-Chloro-β-bromostyrene (related); β-Bromo-p-chlorostyrene (related)
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(4-Chlorophenyl)But-1-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay and impurity profiles. Our commitment to traceability and documentation supports your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.