Description

3-[1-(2-Chloro-6-Fluorophenyl)-2-Nitroethyl]-1H-Indole CAS NO 731003-77-3 is a high-purity, synthetically derived indole derivative characterized by its unique halogenated aromatic and nitroethyl substituents. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, particularly within pharmaceutical research and development. It is primarily required by R&D chemists and process development scientists in the life sciences sector for constructing novel chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its halogenated aromatic structure.
• Organic Synthesis & Material Science: Serves as a versatile precursor for creating complex heterocyclic compounds and specialty chemicals with tailored properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions involving indole scaffolds.

Basic Information

Product Name	3-[1-(2-Chloro-6-Fluorophenyl)-2-Nitroethyl]-1H-Indole
CAS No.	731003-77-3
Molecular Formula	C₁₆H₁₂ClFN₂O₂
Molecular Weight	318.73 g/mol
Synonyms	1H-Indole, 3-[1-(2-chloro-6-fluorophenyl)-2-nitroethyl]-; 3-(1-(2-Chloro-6-fluorophenyl)-2-nitroethyl)-1H-indole; 2-Chloro-6-fluoro-β-(3-indolyl)-β-nitroethylbenzene; (2-Chloro-6-fluorophenyl)(3-indolyl)nitroethane; 731003-77-3
EINECS	Contact for details

Quality Control

Our 3-[1-(1-(2-Chloro-6-Fluorophenyl)-2-Nitroethyl]-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.