Description

4-(4-Chlorophenyl)-5-(2-Methoxyphenyl)-4H-1,2,4-Triazole-3-Thiol is a high-purity, functionalized 1,2,4-triazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical chemical building block for creating complex molecules with tailored properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its triazole-thiol pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides and herbicides, where the triazole core is a common bioactive moiety.
• Material Science Research: Acts as a ligand or functional monomer in the development of specialized polymers, metal-organic frameworks (MOFs), or corrosion inhibitors.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-(4-Chlorophenyl)-5-(2-Methoxyphenyl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	731003-72-8
Molecular Formula	C15H12ClN3OS
Molecular Weight	317.79 g/mol
Synonyms	4-(4-Chlorophenyl)-5-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol; 4-(p-Chlorophenyl)-5-(o-methoxyphenyl)-4H-1,2,4-triazole-3-thiol; 3-Mercapto-4-(4-chlorophenyl)-5-(2-methoxyphenyl)-1,2,4-triazole; 1,2,4-Triazole-3-thiol, 4-(4-chlorophenyl)-5-(2-methoxyphenyl)-; 731003-72-8; 4H-1,2,4-Triazole-3-thiol, 4-(4-chlorophenyl)-5-(2-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenyl)-5-(2-Methoxyphenyl)-4H-1,2,4-Triazole-3-Thiol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.