Description

1-Chloro-Isoquinoline-7-Carboxylic Acid is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Acts as a building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up under cGMP conditions.

Basic Information

Product Name	1-Chloro-Isoquinoline-7-Carboxylic Acid
CAS No.	730971-21-8
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	7-Carboxy-1-chloroisoquinoline; 1-Chloro-7-isoquinolinecarboxylic acid; 1-Chloro-7-carboxyisoquinoline; 1-Chloroisoquinoline-7-carboxylic acid; Isoquinoline-7-carboxylic acid, 1-chloro-; 730971-21-8; 1-Cl-IQ-7-COOH
EINECS	Contact for details

Quality Control

Our 1-Chloro-Isoquinoline-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications from research to commercial-scale cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.