Description

4,7-Epoxy-1H-Isoindole-1,3(2H)-Dione, Hexahydro-5,6-Dihydroxy-2-Methyl-, (3Ar,4R,5S,6R,7S,7As)-Rel- (9Ci) is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This molecule serves as a critical chiral building block and intermediate for the development of complex, biologically active molecules. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides where specific stereoisomers are required for optimal efficacy.
• Fine Chemical Manufacturing: Serves as a versatile building block for synthesizing specialty chemicals, dyes, and functional materials.
• Academic & Industrial Research: A valuable compound for methodological development in organic synthesis, catalysis, and stereochemistry studies.
• Bioconjugate Chemistry: Potential use in the development of linker molecules or payloads for antibody-drug conjugates (ADCs) and other targeted therapies.

Basic Information

Item	Details
Product Name	4,7-Epoxy-1H-Isoindole-1,3(2H)-Dione, Hexahydro-5,6-Dihydroxy-2-Methyl-, (3Ar,4R,5S,6R,7S,7As)-Rel- (9Ci)
CAS No.	730963-39-0
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	rel-(3aR,4R,5S,6R,7S,7aS)-Hexahydro-5,6-dihydroxy-2-methyl-4,7-epoxy-1H-isoindole-1,3(2H)-dione; 2-Methyl-4,7-epoxyhexahydro-5,6-dihydroxy-1H-isoindole-1,3(2H)-dione; (3aR,4R,5S,6R,7S,7aS)-Hexahydro-5,6-dihydroxy-2-methyl-4,7-epoxyisoindole-1,3-dione; Chiral Epoxy Isoindoledione Derivative; Advanced Chiral Building Block; CAS 730963-39-0.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and stereochemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.