Description

3-Amino-5-(2,4-Dichloro-Phenyl)-Thiophene-2-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both amino and ester functional groups on a thiophene core, makes it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its dichlorophenyl and thiophene motifs.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and advanced dyes due to its electron-rich thiophene structure.
• Chemical Biology: Employed as a molecular probe or a tag in bioconjugation chemistry to study biological processes.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specialized heterocyclic chemistry.

Basic Information

Product Name	3-Amino-5-(2,4-Dichloro-Phenyl)-Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	730949-95-8
Molecular Formula	C13H11Cl2NO2S
Molecular Weight	316.20 g/mol
Synonyms	Ethyl 3-Amino-5-(2,4-dichlorophenyl)thiophene-2-carboxylate; 3-Amino-5-(2,4-dichlorophenyl)-2-thiophenecarboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 3-amino-5-(2,4-dichlorophenyl)-, ethyl ester; Ethyl 3-amino-5-(2,4-dichlorophenyl)thiophene-2-carboxylate; 730949-95-8; AKOS BRN 1253; 3-Amino-5-(2,4-dichlorophenyl)thiophene-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Amino-5-(2,4-Dichloro-Phenyl)-Thiophene-2-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.