Description

3-Amino-5-(3-Nitro-Phenyl)-Thiophene-2-Carboxylic Acid Ethyl Ester is a high-purity, multifunctional heterocyclic building block of significant importance in advanced organic synthesis. Its molecular architecture, featuring both amino and nitro functional groups on a thiophene core, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene unit.
• Dye and Pigment Synthesis: Employed in the creation of specialized dyes and pigments where the nitro and amino groups allow for color tuning and stability.
• Chemical Biology Probes: Utilized in the design of molecular probes and sensors for studying biological processes.

Basic Information

Product Name	3-Amino-5-(3-Nitro-Phenyl)-Thiophene-2-Carboxylic Acid Ethyl Ester
CAS No.	730949-83-4
Molecular Formula	C13H12N2O4S
Molecular Weight	292.31 g/mol
Synonyms	Ethyl 3-Amino-5-(3-nitrophenyl)thiophene-2-carboxylate; 3-Amino-5-(3-nitrophenyl)-2-thiophenecarboxylic Acid Ethyl Ester; 730949-83-4; 3-Nitrophenyl Thiophene Carboxylate Ester; 3'-Nitro-3-aminothiophene-2-carboxylic acid ethyl ester; 5-(3-Nitrophenyl)-3-aminothiophene-2-carboxylic Acid Ethyl Ester; Thiophene Building Block 730949-83-4
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(3-Nitro-Phenyl)-Thiophene-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.