Description

2-(2,4-Dimethoxy-Phenylamino)-Thiazole-4-Carboxylic Acid is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that leverage its unique thiazole-carboxylic acid scaffold.
• Material Science: Serves as a precursor for creating functional organic molecules used in electronic materials or as ligands in catalysis.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical reactions.
• Peptidomimetics: The carboxylic acid functionality makes it suitable for incorporation into peptide-like structures to modulate biological activity.
• Chemical Biology Probes: Useful for synthesizing tool compounds to study biological processes and identify new therapeutic targets.

Basic Information

Product Name	2-(2,4-Dimethoxy-Phenylamino)-Thiazole-4-Carboxylic Acid
CAS No.	728918-51-2
Molecular Formula	C₁₂H₁₂N₂O₄S
Molecular Weight	280.30 g/mol
Synonyms	2-[(2,4-Dimethoxyphenyl)amino]-1,3-thiazole-4-carboxylic acid; 2-(2,4-Dimethoxyanilino)-4-thiazolecarboxylic acid; 4-Thiazolecarboxylic acid, 2-[(2,4-dimethoxyphenyl)amino]-; 728918-51-2; 2-(2,4-Dimethoxy-phenylamino)-thiazole-4-carboxylic acid; Thiazole-4-carboxylic acid, 2-[(2,4-dimethoxyphenyl)amino]-; 2-(2,4-Dimethoxyphenylamino)thiazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(2,4-Dimethoxy-Phenylamino)-Thiazole-4-Carboxylic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.