Description

6-Bromo-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carbaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its reactive aldehyde and halogenated imidazopyridine scaffold, enabling the construction of complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, leveraging its imidazopyridine core which is prevalent in bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and aldehyde functionalities allow for diverse structural modifications.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, or photoactive materials due to its conjugated system.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying biological processes and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form carbon-carbon bonds.
• Library Synthesis for HTS: An ideal starting material for generating diverse compound libraries used in high-throughput screening (HTS) campaigns in drug discovery.

Basic Information

Product Name	6-Bromo-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carbaldehyde
CAS No.	728864-58-2
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	6-Bromo-2-methylimidazo[1,2-a]pyridine-3-carboxaldehyde; 2-Methyl-6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde; Imidazo[1,2-a]pyridine-3-carbaldehyde, 6-bromo-2-methyl-; 728864-58-2; 6-Bromo-2-methyl-3-formylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality control includes identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of specific impurities. Certificates of Analysis (COA) detailing all test results are available upon request. We adhere to cGMP principles for the manufacture of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.