Description

1-Benzyl-5-Fluoro-1H-Indole-3-Carbaldehyde is a high-purity fluorinated indole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its versatile aldehyde functionality and substituted indole core, which serve as key building blocks for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, leveraging the biological activity of the fluorinated indole scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, organic semiconductors, and fluorescent dyes.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagging reagent due to its reactive aldehyde group, useful for bioconjugation and labeling studies.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry, including cross-coupling reactions and heterocyclic chemistry research.

Basic Information

Product Name	1-Benzyl-5-Fluoro-1H-Indole-3-Carbaldehyde
CAS No.	728024-41-7
Molecular Formula	C₁₆H₁₂FNO
Molecular Weight	253.27 g/mol
Synonyms	5-Fluoro-1-benzylindole-3-carboxaldehyde; 1-Benzyl-5-fluoroindole-3-carbaldehyde; 3-Formyl-1-benzyl-5-fluoroindole; 1-Benzyl-5-fluoro-1H-indole-3-carboxaldehyde; 728024-41-7; 5-Fluoro-1-benzyl-1H-indole-3-carbaldehyde; 1H-Indole-3-carboxaldehyde, 1-benzyl-5-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 1-Benzyl-5-Fluoro-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.