Description

Indolizine, Octahydro-5,7-Dimethyl-, (5S,7S,8Ar)- (9Ci) is a high-purity, stereochemically defined indolizine derivative, a class of compounds valued for their complex heterocyclic structure. This specific isomer is a critical advanced intermediate for synthesizing novel pharmaceuticals and fine chemicals, where precise stereochemistry is essential for biological activity and process control. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex molecular scaffold for novel modes of action.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric catalysis.
• Material Science: Investigated as a monomer or additive for creating advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Indolizine, Octahydro-5,7-Dimethyl-, (5S,7S,8Ar)- (9Ci)
CAS No.	727985-51-5
Molecular Formula	C12H21N
Molecular Weight	179.30 g/mol
Synonyms	(5S,7S,8aR)-Octahydro-5,7-dimethylindolizine; (5S,7S,8aR)-5,7-Dimethyloctahydroindolizine; 5,7-Dimethyloctahydroindolizine, (5S,7S,8aR)-; Indolizine, octahydro-5,7-dimethyl-, (5S,7S,8aR)-; (5S,7S,8aR)-5,7-Dimethyl-1,2,3,5,6,7,8,8a-octahydroindolizine; Stereoisomer of octahydro-5,7-dimethylindolizine
EINECS	Contact for details

Quality Control

Our Indolizine, Octahydro-5,7-Dimethyl-, (5S,7S,8Ar)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC to confirm stereochemical purity and identity verification by NMR and MS. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, chiral excess, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.