Description

Indolizine, Octahydro-5,7-Dimethyl-, (5R,7R,8As)- (9Ci) is a high-purity, stereochemically defined indolizine derivative, a versatile heterocyclic scaffold of significant interest in advanced organic synthesis. Its precise stereochemistry and defined molecular architecture make it a critical chiral building block for the development of novel pharmaceuticals and agrochemicals. This compound is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the indolizine core can impart specific biological activity.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Material Science Research: Investigated as a monomer or functional unit for creating specialty polymers with unique optical or electronic properties.
• Academic & Process Chemistry: A valuable tool for method development and studying structure-activity relationships (SAR) in complex molecule synthesis.

Basic Information

Item	Detail
Product Name	Indolizine, Octahydro-5,7-Dimethyl-, (5R,7R,8As)- (9Ci)
CAS No.	727985-45-7
Molecular Formula	C12H21N
Molecular Weight	179.30 g/mol
Synonyms	(5R,7R,8aS)-Octahydro-5,7-dimethylindolizine; (5R,7R,8aS)-5,7-Dimethyloctahydroindolizine; 5,7-Dimethyloctahydroindolizine, (5R,7R,8aS)-; Indolizine, octahydro-5,7-dimethyl-, (5R,7R,8aS)-; (8aS)-5,7-Dimethyloctahydroindolizine; cis-5,7-Dimethyloctahydroindolizine (stereospecific)
EINECS	Contact for details

Quality Control

Our Indolizine, Octahydro-5,7-Dimethyl-, (5R,7R,8As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and stereochemical purity consistent with research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.