Description

Indolizine, Octahydro-5,7-Dimethyl-, (5R,7R,8Ar)- (9Ci) is a stereochemically defined, saturated indolizine derivative, a valuable chiral building block in advanced organic synthesis. Its rigid, fused bicyclic structure and defined stereochemistry make it a critical intermediate for constructing complex molecules with high precision. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its structural framework can contribute to biological activity.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing sophisticated chiral ligands used in enantioselective catalytic reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring specific stereochemistry.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in heterocyclic and stereoselective chemistry.

Basic Information

Product Name	Indolizine, Octahydro-5,7-Dimethyl-, (5R,7R,8Ar)- (9Ci)
CAS No.	727985-44-6
Molecular Formula	C12H21N
Molecular Weight	179.30 g/mol
Synonyms	(5R,7R,8aR)-Octahydro-5,7-dimethylindolizine; (5R,7R,8aR)-5,7-Dimethyloctahydroindolizine; 5,7-Dimethyloctahydroindolizine, (5R,7R,8aR)-; Indolizine, octahydro-5,7-dimethyl-, (5R,7R,8aR)-; (5R,7R,8aR)-5,7-Dimethyl-1,2,3,5,6,7,8,8a-octahydroindolizine; Chiral Octahydrodimethylindolizine; Stereoisomer of Octahydro-5,7-dimethylindolizine
EINECS	Contact for details

Quality Control

Our Indolizine, Octahydro-5,7-Dimethyl-, (5R,7R,8Ar)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC-MS, and NMR to confirm identity, stereochemical purity, and chemical assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.