Description

3(2H)-Indolizinone,Hexahydro-5-Methyl-7-Methylene-,(5R,8As)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This specialized chemical serves as a critical chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and complex natural product analogs. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures with precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used as a building block for creating novel, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis: Employed in the development of new chiral ligands and catalysts for stereoselective synthesis.
• Natural Product Analog Synthesis: Serves as a core structural motif for synthesizing analogs of complex indolizidine and related alkaloids for biological evaluation.
• Material Science Research: Investigated as a precursor for advanced organic materials and liquid crystals due to its rigid, fused-ring structure.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in heterocyclic and stereoselective chemistry.

Basic Information

Product Name	3(2H)-Indolizinone,Hexahydro-5-Methyl-7-Methylene-,(5R,8As)-(9Ci)
CAS No.	727985-41-3
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(5R,8aS)-Hexahydro-5-methyl-7-methylidene-3H-indolizin-3-one; (5R,8aS)-5-Methyl-7-methylenehexahydro-3(2H)-indolizinone; 3(2H)-Indolizinone, hexahydro-5-methyl-7-methylene-, (5R,8aS)-; (5R,8aS)-5-Methyl-7-methylideneoctahydroindolizin-3-one; Stereoisomer of indolizinone derivative; Chiral indolizinone building block
EINECS	Contact for details

Quality Control

Every batch of our 3(2H)-Indolizinone,Hexahydro-5-Methyl-7-Methylene-,(5R,8As)-(9Ci) is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, Chiral HPLC, and NMR to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results for assay, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.