Description

2-(2-Chloro-Acetylamino)-5-Isopropyl-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific thiophene-based molecular architecture. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a reliable building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in research for creating new active ingredients for crop protection products.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex heterocyclic compounds.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of target molecules.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-5-Isopropyl-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	726152-04-1
Molecular Formula	C13H18ClNO3S
Molecular Weight	303.80 g/mol
Synonyms	Ethyl 2-[(2-chloroacetyl)amino]-5-(propan-2-yl)thiophene-3-carboxylate; 2-(2-Chloroacetamido)-5-isopropylthiophene-3-carboxylic acid ethyl ester; 5-Isopropyl-2-[(2-chloroacetyl)amino]thiophene-3-carboxylic acid ethyl ester; CAS 726152-04-1; Thiophene-3-carboxylic acid, 2-[(2-chloroacetyl)amino]-5-(1-methylethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-(2-Chloro-Acetylamino)-5-Isopropyl-Thiophene-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.