Description

(5,6-Dimethyl-4-Oxo-3,4-Dihydro-Thieno[2,3-D]Pyrimidin-2-Yl)-Acetonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its fused thienopyrimidine core structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel, small-molecule therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for targeting kinase-related pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step manufacturing process of potent active drug substances.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and cellular signaling mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(5,6-Dimethyl-4-Oxo-3,4-Dihydro-Thieno[2,3-D]Pyrimidin-2-Yl)-Acetonitrile
CAS No.	726151-97-9
Molecular Formula	C11H9N3OS
Molecular Weight	231.27 g/mol
Synonyms	2-(5,6-Dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)acetonitrile; Thieno[2,3-d]pyrimidine-2-acetonitrile, 3,4-dihydro-5,6-dimethyl-4-oxo-; 726151-97-9; 5,6-Dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-acetonitrile; (5,6-Dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of (5,6-Dimethyl-4-Oxo-3,4-Dihydro-Thieno[2,3-D]Pyrimidin-2-Yl)-Acetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is released with a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, and specifications can be aligned with client-specific pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.