Description

2-Amino-n-(2-Chlorophenyl)-4,5,6,7,8,9-Hexahydrocycloocta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new drug candidates, especially within medicinal chemistry programs targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Development: Incorporated into the synthesis of potential Active Pharmaceutical Ingredients (APIs) for preclinical and clinical development.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for synthetic organic chemistry and heterocyclic compound research.

Basic Information

Product Name	2-Amino-n-(2-Chlorophenyl)-4,5,6,7,8,9-Hexahydrocycloocta[B]Thiophene-3-Carboxamide
CAS No.	726144-24-7
Molecular Formula	C19H21ClN2OS
Molecular Weight	360.90 g/mol
Synonyms	2-Amino-N-(2-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxamide; 2-Amino-N-(2-chlorophenyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxylic acid amide; Cycloocta[b]thiophene-3-carboxamide, 2-amino-N-(2-chlorophenyl)-4,5,6,7,8,9-hexahydro-; 726144-24-7; CAS 726144-24-7
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(2-Chlorophenyl)-4,5,6,7,8,9-Hexahydrocycloocta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports cGMP and ISO standards for pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.