Description

1-[(5-Bromothien-2-Yl)Sulfonyl]Piperazine is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a brominated thiophene sulfonyl moiety with a piperazine ring, making it a versatile intermediate for constructing complex pharmacophores. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and antimicrobials.
• Agrochemical Research: Used in the synthesis of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a building block for functionalized polymers or organic electronic materials due to the electron-rich thiophene and sulfonyl groups.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	1-[(5-Bromothien-2-Yl)Sulfonyl]Piperazine
CAS No.	725688-07-3
Molecular Formula	C9H11BrN2O2S2
Molecular Weight	323.23 g/mol
Synonyms	1-(5-Bromothiophene-2-sulfonyl)piperazine; 5-Bromo-2-piperazin-1-ylsulfonylthiophene; 1-(5-Bromo-2-thienylsulfonyl)piperazine; Piperazine, 1-[(5-bromo-2-thienyl)sulfonyl]-; 725688-07-3; 5-Bromothiophene-2-sulfonyl piperazine; 2-(Piperazine-1-sulfonyl)-5-bromothiophene
EINECS	Contact for details

Quality Control

Our 1-[(5-Bromothien-2-Yl)Sulfonyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.