Description

4-Bromo-3-Chloro-1-Benzothiophene-2-Carbohydrazide is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique benzothiophene core, functionalized with bromo, chloro, and carbohydrazide groups, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Serves as a crucial building block in the creation of novel herbicides, fungicides, and insecticides with potential new modes of action.
• Material Science Research: Used in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials due to its electron-rich thiophene structure.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent tags, photoaffinity labels, or other molecular probes to study biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-Bromo-3-Chloro-1-Benzothiophene-2-Carbohydrazide
CAS No.	725227-19-0
Molecular Formula	C9H6BrClN2OS
Molecular Weight	305.58 g/mol
Synonyms	4-Bromo-3-chlorobenzo[b]thiophene-2-carbohydrazide; 4-Bromo-3-chloro-1-benzothiophene-2-carboxylic acid hydrazide; 4-Bromo-3-chloro-benzo[b]thiophene-2-carboxylic acid hydrazide; 725227-19-0; Benzo[b]thiophene-2-carbohydrazide, 4-bromo-3-chloro-; 4-Bromo-3-chloro-1-benzothiophene-2-carboxhydrazide
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-1-Benzothiophene-2-Carbohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.