Description

2-Amino-n-(4-Methylbenzyl)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), where structural precision and batch-to-batch consistency are paramount. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Custom Synthesis Starting Material: Provides a specialized starting point for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	2-Amino-n-(4-Methylbenzyl)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide
CAS No.	725226-42-6
Molecular Formula	C17H20N2OS
Molecular Weight	300.42 g/mol
Synonyms	2-Amino-N-[(4-methylphenyl)methyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide; 2-Amino-N-(4-methylbenzyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 4,5,6,7-Tetrahydro-2-amino-N-(4-methylbenzyl)benzo[b]thiophene-3-carboxamide; 725226-42-6; 2-Amino-N-(p-methylbenzyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide; AMB-DHCPT-Carboxamide
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(4-Methylbenzyl)-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete traceability are provided for every shipment, and we support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.