Description

Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-8,9-Dihydroxy-, (10Bs)- (9Ci) is a high-purity, complex heterocyclic compound of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and chiral building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by pharmaceutical R&D laboratories and specialty chemical manufacturers engaged in the synthesis of complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-cancer therapies.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct fused polycyclic structures due to its unique pyrroloisoquinoline scaffold.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in studies exploring new catalytic methodologies.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in synthetic organic chemistry and heterocyclic chemistry.

Basic Information

Product Name	Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-8,9-Dihydroxy-, (10Bs)- (9Ci)
CAS No.	724706-17-6
Molecular Formula	C₁₃H₁₃NO₃
Molecular Weight	231.25 g/mol
Synonyms	(10bS)-1,5,6,10b-Tetrahydro-8,9-dihydroxypyrrolo[2,1-a]isoquinolin-3(2H)-one; (S)-1,5,6,10b-Tetrahydro-8,9-dihydroxy-2H-pyrrolo[2,1-a]isoquinolin-3-one; 8,9-Dihydroxy-1,5,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-3(2H)-one, (10bS)-; Pyrrolo[2,1-a]isoquinoline-3(2H)-one, 1,5,6,10b-tetrahydro-8,9-dihydroxy-, (10bS)-; (S)-8,9-Dihydroxy-1,2,5,6,10,10b-hexahydropyrrolo[2,1-a]isoquinolin-3-one
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[2,1-A]Isoquinolin-3(2H)-One, 1,5,6,10B-Tetrahydro-8,9-Dihydroxy-, (10Bs)- (9Ci) adheres to stringent GMP-like guidelines to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and chiral analysis for enantiomeric excess. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.