Description

5-Thiazoleacetic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is a high-purity, protected amino acid derivative featuring a thiazole heterocycle, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules where the thiazole moiety and protected amino functionality are key structural elements.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the thiazole ring contributes to biological activity.
• Peptide Mimetics & Bioconjugation: The carboxylic acid and protected amine groups make it valuable for creating peptide analogs and for bioconjugation strategies in medicinal chemistry.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science applications.
• Chemical Biology Research: Employed as a probe or building block in studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-fidelity intermediates.

Basic Information

Product Name	5-Thiazoleacetic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-
CAS No.	723278-39-5
Molecular Formula	C10H14N2O4S
Molecular Weight	258.29 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-1,3-thiazole-5-acetic acid; 2-((tert-Butoxycarbonyl)amino)thiazole-5-acetic acid; Boc-Amino-thiazole-acetic acid; 5-Thiazoleacetic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-; 2-(Boc-amino)thiazole-5-acetic acid; tert-Butyl (5-carboxymethylthiazol-2-yl)carbamate; (2-((tert-Butoxycarbonyl)amino)thiazol-5-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 5-Thiazoleacetic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.