Description

2-(2-Chloro-Acetylamino)-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-3-Carboxylic Acid (4-Chloro-Phenyl)-Amide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system or with specific receptor activity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks containing tetrahydrobenzothiophene and amide functionalities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional laboratories for studying novel chemical reactions and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	2-(2-Chloro-Acetylamino)-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-3-Carboxylic Acid (4-Chloro-Phenyl)-Amide
CAS No.	721892-21-3
Molecular Formula	C19H18Cl2N2O2S
Molecular Weight	409.33 g/mol
Synonyms	2-[(2-Chloroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, N-(4-Chlorophenyl)-; 2-(2-Chloroacetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (4-chlorophenyl)amide; 721892-21-3; 4,5,6,7-Tetrahydro-2-[(2-chloroacetyl)amino]benzo[b]thiophene-3-carboxylic acid 4-chloroanilide; N-(4-Chlorophenyl)-2-[(2-chloroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-4,5,6,7-Tetrahydro-Benzo[B]Thiophene-3-Carboxylic Acid (4-Chloro-Phenyl)-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.