Description

8-Chloro-4-Methyl-3-Phenylcoumarin is a functionalized coumarin derivative, a versatile heterocyclic scaffold of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the coumarin core is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging the bioactivity of substituted coumarins.
• Fluorescent Dye & Sensor Precursor: Acts as a starting material for synthesizing advanced organic fluorophores and chemosensors due to the tunable photophysical properties of the coumarin structure.
• Organic Electronic Materials: Investigated as a component or precursor in the development of organic light-emitting diodes (OLEDs) or photovoltaic materials.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in organic chemistry, such as novel cyclization or cross-coupling reactions.
• Cosmetic Ingredient Synthesis: Potentially used in the research phase for creating UV-absorbing or skin-conditioning agents.

Basic Information

Product Name	8-Chloro-4-Methyl-3-Phenylcoumarin
CAS No.	720672-82-2
Molecular Formula	C₁₆H₁₁ClO₂
Molecular Weight	270.71 g/mol
Synonyms	8-Chloro-4-methyl-3-phenyl-2H-chromen-2-one; 3-Phenyl-8-chloro-4-methylcoumarin; 2H-1-Benzopyran-2-one, 8-chloro-4-methyl-3-phenyl-; 8-Chloro-4-methyl-3-phenyl-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 8-Chloro-4-Methyl-3-Phenylcoumarin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and physical characteristics. Our quality system supports development and scale-up needs from laboratory to pilot plant quantities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.