Description

[1,4'-Bipiperidine]-1'-Carbonyl-D10 Chloride Hydrochloride is a deuterated building block and chemical intermediate of significant value in advanced research and development. This compound matters for its role in the synthesis of isotopically labeled molecules, which are critical for pharmacokinetic, metabolic, and mechanistic studies. It is primarily needed by pharmaceutical R&D teams, agrochemical scientists, and specialized contract research organizations (CROs) engaged in drug discovery and development.

Application

• As a deuterated synthetic intermediate in the preparation of isotopically labeled active pharmaceutical ingredients (APIs) for use as internal standards in LC-MS/MS analysis.
• In drug metabolism and pharmacokinetics (DMPK) studies to trace the metabolic fate of drug candidates and understand their biological pathways.
• For the research and development of novel bioactive compounds targeting neurological disorders, leveraging the bipiperidine scaffold.
• In academic and industrial research focused on medicinal chemistry, chemical biology, and probe development.
• As a specialized reagent in the synthesis of radioligands and imaging agents for positron emission tomography (PET) or single-photon emission computed tomography (SPECT).
• For creating deuterated analogs in agrochemical research to study environmental degradation and metabolic profiles.

Basic Information

Product Name	[1,4'-Bipiperidine]-1'-Carbonyl-D10 Chloride Hydrochloride
CAS No.	718613-22-0
Molecular Formula	C11H10D10Cl2N2O
Molecular Weight	289.26 g/mol
Synonyms	1,4'-Bipiperidine-1'-carbonyl-d10 chloride hydrochloride; 1,4'-Bipiperidine-1'-carbonyl-d10 acid chloride hydrochloride; Perdeuterated [1,4'-Bipiperidine]-1'-Carbonyl Chloride Hydrochloride; 1,1'-Bipiperidine-4-carbonyl-d10 chloride hydrochloride; 4-Piperidinecarbonyl-d10 chloride, 1-(1-piperidinyl)-, hydrochloride; Deuterated Bipiperidine Carbonyl Chloride HCl; (1,4'-Bipiperidin-1'-yl)(oxo)acetic-d10 acid chloride hydrochloride
EINECS	Contact for details

Quality Control

Our [1,4'-Bipiperidine]-1'-Carbonyl-D10 Chloride Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ²H), HPLC, and mass spectrometry, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) with detailed specifications are provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (²H NMR / MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.