Description

Adenosine-2'-13C CAS NO 714950-52-4 is a stable isotope-labeled analog of adenosine, a fundamental nucleoside in biochemistry. This product is essential for advanced research and development in metabolic pathway analysis and quantitative proteomics, providing a critical tool for precise measurement and tracing. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and diagnostic developers working in drug discovery, metabolomics, and biomarker studies.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to study central carbon metabolism in cells, tissues, or microorganisms.
• Drug Metabolism and Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS/MS for the accurate quantification of adenosine and its metabolites in biological samples.
• Nucleic Acid Research: Employed in the synthesis of isotopically labeled oligonucleotides for structural NMR studies and mechanistic investigations.
• Biomarker Discovery: Facilitates the precise quantification of adenosine-related pathways in disease states for diagnostic development.
• Enzyme Kinetics Studies: Used to investigate the mechanisms and kinetics of adenosine-processing enzymes like kinases and deaminases.
• In vitro Diagnostic (IVD) Assay Development: Acts as a critical calibrator or reference material in clinical assay kits.

Basic Information

Product Name	Adenosine-2'-13C
CAS No.	714950-52-4
Molecular Formula	C10H1213CN5O4
Molecular Weight	268.24 g/mol (for 13C1 isotopologue)
Synonyms	2'-13C-Adenosine; Adenosine (2'-13C); 9-β-D-Ribofuranosyladenine-2'-13C; 6-Amino-9-β-D-ribofuranosyl-9H-purine-2'-13C; 13C Labeled Adenosine; Adenosine-2'-carbon-13; Stable Isotope Labeled Adenosine
EINECS	Contact for details

Quality Control

Our Adenosine-2'-13C is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), and identity confirmation. We support compliance with relevant GMP/GLP guidelines for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.