Description

1-Methanesulfonyl-2,3-Dihydro-1 H-Indole-5-Carboxylic Acid is a high-purity, synthetically valuable indole derivative that serves as a critical building block in advanced organic synthesis. Its unique sulfonyl-substituted indoline scaffold makes it a versatile intermediate for constructing complex molecules with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Synthesis: Serves as a versatile building block for synthesizing more complex indole-based heterocycles and functionalized molecules.
• Agrochemical Development: Potential intermediate in the research of novel crop protection agents and pesticides.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental organic chemistry research and custom synthesis projects.

Basic Information

Product Name	1-Methanesulfonyl-2,3-Dihydro-1 H-Indole-5-Carboxylic Acid
CAS No.	712319-44-3
Molecular Formula	C10H11NO4S
Molecular Weight	241.26 g/mol
Synonyms	5-Carboxy-1-(methylsulfonyl)indoline; 1H-Indole-5-carboxylic acid, 2,3-dihydro-1-(methylsulfonyl)-; 1-(Methanesulfonyl)indoline-5-carboxylic acid; 1-Methylsulfonyl-2,3-dihydroindole-5-carboxylic acid; MSI-5-COOH; Indoline-5-carboxylic acid, 1-(methylsulfonyl)-; 712319-44-3
EINECS	Contact for details

Quality Control

Our 1-Methanesulfonyl-2,3-Dihydro-1 H-Indole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material integrity for your most sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.