Description

3-Chloro-n-[(4-Methyl-1-Piperazinyl)Carbonothioyl]-1-Benzothiophene-2-Carboxamide is a specialized heterocyclic organic compound featuring a benzothiophene core functionalized with a thiourea-linked methylpiperazine group. This molecular architecture makes it a valuable high-purity building block and key intermediate in advanced chemical synthesis, particularly for pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel therapeutic candidates and fine-tuning synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Acts as a key intermediate in multi-step organic syntheses for producing complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis projects and process development for client molecules.
• Academic Research: Utilized in university and institutional laboratories for methodological development and exploring new heterocyclic chemistry.

Basic Information

Product Name	3-Chloro-n-[(4-Methyl-1-Piperazinyl)Carbonothioyl]-1-Benzothiophene-2-Carboxamide
CAS No.	712318-16-6
Molecular Formula	C15H15ClN4OS2
Molecular Weight	382.89 g/mol
Synonyms	3-Chloro-N-[(4-methylpiperazin-1-yl)carbamothioyl]-1-benzothiophene-2-carboxamide; 3-Chloro-1-benzothiophene-2-carboxylic acid N'-(4-methyl-1-piperazinyl)thioureide; N-[(4-Methyl-1-piperazinyl)carbonothioyl]-3-chloro-1-benzothiophene-2-carboxamide; 3-Chloro-1-benzothiophene-2-carbothioic acid, N-(4-methyl-1-piperazinyl)amide; CAS 712318-16-6; Benzothiophene-2-carboxamide, 3-chloro-N-[(4-methyl-1-piperazinyl)carbonothioyl]-; Thiourea, N-(3-chloro-1-benzothiophen-2-ylcarbonyl)-N'-(4-methyl-1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-n-[(4-Methyl-1-Piperazinyl)Carbonothioyl]-1-Benzothiophene-2-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.