Description

Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl- is a high-purity, structurally complex chiral amine derivative of pinane, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. Its rigid bicyclic framework and functional groups make it an essential precursor for developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials. This compound is primarily targeted at R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to leverage its unique stereochemistry for creating high-value, patentable molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Precursor for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Used to create novel chiral ligands for transition metal catalysis, enabling more efficient and sustainable chemical processes.
• Fine Chemical & Flavor/Fragrance Synthesis: Intermediate for producing high-value specialty chemicals, including complex aroma chemicals and natural product analogs.
• Material Science: Monomer or additive for advanced polymeric materials, where its rigid structure can impart specific thermal or mechanical properties.

Basic Information

Product Name	Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl-
CAS No.	705949-10-6
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid; 2-Amino-2,6,6-trimethyl-3-norpinane-3-carboxylic acid; 3-Carboxy-2,6,6-trimethyl-2-aminonorpinane; Pinane-derived amino acid; 2-Amino-2,6,6-trimethyl-3-pinanecarboxylic acid; (1R,2R,5R)-2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid (for specific enantiomer); APIN-ACA
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.