Description

2-Amino-5,7-Difluoro Indole is a high-purity, multi-functional indole derivative distinguished by its unique fluorine substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate (API) for the synthesis of novel, biologically active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation, fluorinated pesticides and herbicides with enhanced activity and environmental profile.
• Organic Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and functional materials in academic and industrial research.
• Fluorescent Probe Development: The indole core with amino and fluoro groups makes it a candidate for developing sensors and imaging agents.
• Material Science: Potential intermediate for synthesizing specialty polymers and electronic materials requiring specific fluorinated motifs.

Basic Information

Product Name	2-Amino-5,7-Difluoro Indole
CAS No.	705248-90-4
Molecular Formula	C8H6F2N2
Molecular Weight	168.14 g/mol
Synonyms	5,7-Difluoro-1H-indol-2-amine; 1H-Indole-2-amine, 5,7-difluoro-; 2-Amino-5,7-difluoro-1H-indole; 5,7-Difluoroindol-2-amine; 2-Amino-5,7-difluoroindole; AI3-71078; ZINC000103079757
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5,7-Difluoro Indole is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.