Description

1-Cyclopentene-1-Methanol, 4-(Dimethylphenylsilyl)-5-[(Phenylmethoxy)Methyl]-, (4S,5R)- is a high-value, stereochemically defined chiral building block featuring both silyl and benzyl-protected alcohol functionalities. This compound matters as a sophisticated intermediate in asymmetric synthesis, enabling the construction of complex molecular architectures with precise stereocontrol. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Asymmetric Synthesis: Serves as a versatile precursor in stereoselective reactions, including cross-coupling, oxidation, and functional group transformations.
• Agrochemical Research: Used in the synthesis of advanced, biologically active molecules for crop protection and pest management.
• Ligand and Catalyst Development: A potential starting material for creating novel chiral ligands and organocatalysts used in enantioselective catalysis.
• Material Science Precursor: Can be utilized in the development of specialty polymers and advanced organic materials with specific stereochemical properties.
• Academic & Contract Research: Essential for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	1-Cyclopentene-1-Methanol, 4-(Dimethylphenylsilyl)-5-[(Phenylmethoxy)Methyl]-, (4S,5R)-
CAS No.	701278-09-3
Molecular Formula	C22H28O2Si
Molecular Weight	352.55 g/mol
Synonyms	(4S,5R)-4-(Dimethylphenylsilyl)-5-[(phenylmethoxy)methyl]-1-cyclopentene-1-methanol; (4S,5R)-4-(Dimethyl(phenyl)silyl)-5-((benzyloxy)methyl)cyclopent-1-ene-1-carbaldehyde (reduction product); Chiral Cyclopentene Silyl Ether; (1R,2S)-rel-2-[(Benzyloxy)methyl]-1-[(dimethylphenylsilyl)methyl]cyclopent-3-ene-1-carbaldehyde (related isomer); Phenylmethyl (4S,5R)-4-(dimethylphenylsilyl)-5-(hydroxymethyl)-1-cyclopentene-1-carboxylate derivative; Advanced Chiral Building Block 701278-09-3.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 1-Cyclopentene-1-Methanol, 4-(Dimethylphenylsilyl)-5-[(Phenylmethoxy)Methyl]-, (4S,5R)- is characterized using advanced analytical techniques (NMR, HPLC, GC) to confirm identity, stereochemical purity (enantiomeric excess), and chemical purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.