Description

Bromoethyl 1,2-Dipalmitoyl-Rac-Glycero-3-Phosphate CAS NO 79907-73-6 is a synthetic, high-purity phospholipid derivative, specifically a bromoethylated phosphatidic acid analog. This compound is a critical building block in advanced organic synthesis and lipid research, enabling the controlled introduction of reactive bromoethyl groups into complex lipid structures. It is primarily utilized by pharmaceutical researchers, lipid chemists, and material scientists for developing novel drug delivery systems, creating functionalized liposomes, and synthesizing specialized phospholipid conjugates.

Application

• Lipid Nanoparticle (LNP) & Liposome Formulation: As a functionalized phospholipid precursor for creating targeted or stimuli-responsive drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Phospholipid Conjugate Synthesis: Serving as a key intermediate for attaching targeting ligands (e.g., peptides, antibodies) or reporter molecules (e.g., fluorescent dyes) to lipid membranes via the reactive bromoethyl group.
• Model Membrane Studies: Used in biophysical research to incorporate specific, modifiable functional groups into artificial lipid bilayers to study membrane dynamics and protein-lipid interactions.
• Prodrug Development: Acting as a linker moiety for constructing phospholipid-based prodrugs, where the active pharmaceutical ingredient is covalently attached for controlled release.
• Biomimetic Material Science: A component in the synthesis of advanced biomaterials that mimic cellular membranes for biosensing or tissue engineering applications.
• Chemical Biology Probes: Synthesis of activity-based probes to label or study enzymes involved in lipid metabolism and signaling pathways.

Basic Information

Item	Detail
Product Name	Bromoethyl 1,2-Dipalmitoyl-Rac-Glycero-3-Phosphate
CAS No.	79907-73-6
Molecular Formula	C₃₇H₇₂BrO₈P
Molecular Weight	731.83 g/mol
Synonyms	2-Bromoethyl 1,2-Dipalmitoyl-rac-glycero-3-phosphate; 2-Bromoethyl Dipalmitoyl Phosphatidate; rac-1,2-Dipalmitoyl-3-phosphatidic acid 2-bromoethyl ester; Bromoethyl DPPA; DPPA-Bromoethyl ester; 1,2-Dihexadecanoyl-rac-glycero-3-phospho-2-bromoethanol; PA(16:0/16:0)-BrEt; Bromoethyl phosphatidic acid (16:0 PA-Br)
EINECS	Contact for details

Quality Control

Our Bromoethyl 1,2-Dipalmitoyl-Rac-Glycero-3-Phosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to maintain stability. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent exposure to atmospheric moisture. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, dichloromethane, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.