Description

2,2,2-Trifluoro-1-(4-Methyl-3-Indolyl)Ethanone is a specialized fluorinated indole derivative, a key building block in advanced organic synthesis. Its trifluoroacetyl group attached to the indole scaffold makes it a valuable precursor for creating complex molecules with enhanced biological activity and metabolic stability. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of novel drug candidates, particularly in oncology and CNS (Central Nervous System) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and target binding.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and organic electronic materials with unique fluorinated properties.
• Fluorescent Probe Development: The indole core can be utilized to build fluorophores and molecular probes for biochemical sensing and imaging applications.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Methyl-3-Indolyl)Ethanone
CAS No.	79878-01-6
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	1-(4-Methyl-1H-indol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-methyl-1H-indol-3-yl)ethanone; 4-Methyl-3-trifluoroacetylindole; 3-Trifluoroacetyl-4-methylindole; TFMI; 79878-01-6; Trifluoroacetyl-4-methylindole
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Trifluoro-1-(4-Methyl-3-Indolyl)Ethanone is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for research and scale-up applications. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.