Description

(R)-2-(+)-Amino-1,1,2-Triphenylethanol is a high-value chiral amino alcohol building block, distinguished by its three phenyl groups and single stereogenic center. This compound matters as a versatile chiral auxiliary and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures with high stereoselectivity.

Application

• As a chiral ligand or catalyst in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• As a key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• As a resolving agent for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• In academic and industrial research for developing novel methodologies in stereoselective synthesis.
• As a precursor for synthesizing more complex chiral auxiliaries and organocatalysts.
• In the development of chiral stationary phases for analytical and preparative chromatography.

Basic Information

Product Name	(R)-2-(+)-Amino-1,1,2-Triphenylethanol
CAS No.	79868-79-4
Molecular Formula	C20H19NO
Molecular Weight	289.37 g/mol
Synonyms	(R)-(+)-2-Amino-1,1,2-triphenylethanol; (R)-2-Amino-1,1,2-triphenylethanol; (+)-(R)-2-Amino-1,1,2-triphenylethanol; (1R)-2-Amino-1,1,2-triphenylethanol; (R)-1,1,2-Triphenyl-2-aminoethanol; ATE; (R)-α,α-Diphenyl-2-phenylethanolamine; (R)-2-Amino-1,1,2-triphenylethanol-1-ol
EINECS	Contact for details

Quality Control

Our (R)-2-(+)-Amino-1,1,2-Triphenylethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC purity and chiral HPLC assay to confirm enantiomeric excess (e.e.). A detailed Certificate of Analysis (COA) is supplied with each batch, documenting identity, purity, and specific rotation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Specific Rotation [α]D20	+40° to +45° (c=1 in Methanol)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.