Description

(S)-(-)-Indoline-2-Carboxylic Acid CAS NO 79815-20-6 is a high-purity, non-proteinogenic amino acid derivative characterized by its chiral indoline scaffold. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules. It is essential for research and production in medicinal chemistry, particularly for developing active pharmaceutical ingredients (APIs) with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, receptor antagonists, and other biologically active compounds.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereocenters.
• Peptidomimetics Research: Incorporated into peptide backbones to create novel peptidomimetic drug candidates with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Agrochemical Synthesis: Acts as a precursor for chiral active ingredients in advanced crop protection agents.
• Academic & Industrial R&D: Serves as a standard or reagent in method development and discovery chemistry within contract research organizations (CROs) and pharmaceutical companies.

Basic Information

Product Name	(S)-(-)-Indoline-2-Carboxylic Acid
CAS No.	79815-20-6
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(2S)-Indoline-2-carboxylic acid; (S)-2-Carboxyindoline; L-Indoline-2-carboxylic acid; (-)-Indoline-2-carboxylic acid; (S)-Indoline-2-carboxylic acid; 79815-20-6; (S)-2,3-Dihydro-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-(-)-Indoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.