Description

(S)-2,3,4,9-Tetrahydro-1H-Pyridol[3,4-B]-3-Indolecarboxylic Acid Methyl Ester is a high-purity chiral indole derivative, a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its role as a critical building block for constructing complex molecules with specific stereochemistry, essential for developing new therapeutic agents. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and process chemistry for novel APIs.
• Asymmetric Synthesis: Used in stereoselective reactions to introduce the (S)-configured tetrahydro-β-carboline scaffold into target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Investigated for its potential biological activity and interactions within enzymatic systems.

Basic Information

Product Name	(S)-2,3,4,9-Tetrahydro-1H-Pyridol[3,4-B]-3-Indolecarboxylic Acid Methyl Ester
CAS No.	79815-18-2
Molecular Formula	C14H16N2O2
Molecular Weight	244.29 g/mol
Synonyms	(S)-Methyl 1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylate; (S)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester; (S)-Tetrahydro-β-carboline-3-carboxylic acid methyl ester; (S)-THBC-COOH methyl ester; (S)-MeTHBC; (S)-Methyl tetrahydro-β-carboline-3-carboxylate; (S)-3-(Methoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
EINECS	Contact for details

Quality Control

Our (S)-2,3,4,9-Tetrahydro-1H-Pyridol[3,4-B]-3-Indolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.