Description

Ketorfanol is a potent, synthetic opioid analgesic compound with significant research and pharmaceutical development interest. Its primary value lies in its high-affinity binding to opioid receptors, making it a critical compound for studying pain pathways and developing novel therapeutic agents. This product is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on central nervous system (CNS) drug discovery and neuropharmacology.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate in the development of new analgesic medications.
• Neuropharmacology Studies: Used in preclinical research to investigate opioid receptor function, ligand binding, and signal transduction mechanisms.
• Analytical Chemistry: Serves as a high-purity standard for method development and validation in chromatographic analysis (HPLC, GC-MS) within forensic and clinical toxicology labs.
• Biochemical Assays: Employed in in vitro assays to screen for new compounds with opioid activity or to study receptor-ligand interactions.
• Chemical Synthesis: Acts as a key synthetic intermediate or building block for creating novel chemical entities with potential therapeutic applications.

Basic Information

Product Name	Ketorfanol
CAS No.	79798-39-3
Molecular Formula	C₂₄H₃₁NO₄
Molecular Weight	397.51 g/mol
Synonyms	Ketorfanol; (-)-Ketorfanol; (5α,7α,8β)-17-(Cyclopropylmethyl)-6,14-endo-etheno-7,8-dihydro-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α,17-trimethyl-α-propyl-6,14-ethenomorphinan-7-methanol; U-50488H analog; U-62066; Spiradoline analog
EINECS	Contact for details

Quality Control

Our Ketorfanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification (IR, NMR), assay (HPLC), and impurity profiling to meet exacting research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use within the primary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.