Description

L-Cysteine, S-Benzyl (3-13C) is a stable-isotope labeled derivative of the amino acid cysteine, where the carbon atom at the 3-position is enriched with the 13C isotope. This compound is a critical building block for advanced research and development, enabling precise metabolic pathway tracing and structural elucidation in complex biochemical systems. It is essential for scientists in pharmaceutical development, proteomics, and metabolic research who require high-purity, isotopically labeled precursors for mass spectrometry, NMR studies, and the synthesis of labeled peptides and proteins.

Application

• Isotopic Tracer Studies: Used as a 13C-labeled precursor for tracking cysteine metabolism and incorporation into peptides, proteins, and glutathione in biological systems.
• Pharmaceutical Research & Development: A key intermediate in the synthesis of isotopically labeled drug candidates and metabolites for pharmacokinetic and pharmacodynamic studies.
• Proteomics & Mass Spectrometry: Enables accurate quantification and identification of cysteine-containing peptides and proteins using advanced mass spectrometry techniques like LC-MS/MS.
• NMR Spectroscopy: Serves as a valuable tool for structural biology, providing a non-radioactive label for probing protein structure, dynamics, and interactions via Nuclear Magnetic Resonance.
• Biochemical Pathway Analysis: Facilitates the detailed study of sulfur metabolism, redox regulation, and biosynthetic pathways in cells and organisms.
• Synthesis of Labeled Biomolecules: Employed in the custom synthesis of other 13C-labeled amino acids, peptides, and specialized research chemicals.

Basic Information

Product Name	L-Cysteine, S-Benzyl (3-13C)
CAS No.	79761-09-4
Molecular Formula	C10H13NO2S * (13C at position 3)
Molecular Weight	~211.28 g/mol (13C adjusted)
Synonyms	(S)-2-Amino-3-((benzylthio)(13C))propanoic acid; L-3-((Benzylthio)(13C))alanine; S-Benzyl-L-cysteine-3-13C; S-Benzylcysteine-3-13C; 13C Labeled S-Benzyl-L-cysteine; 13C-L-Cysteine, S-benzyl-; Bzl-Cys(13C)-OH; [3-13C]-S-Benzyl-L-cysteine
EINECS	Contact for details

Quality Control

Our L-Cysteine, S-Benzyl (3-13C) is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry to confirm identity, isotopic enrichment (typically >99 atom % 13C), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity and stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.