Description

S-(3-Nitro-2-Pyridinesulfenyl)Cysteine is a specialized cysteine derivative featuring a nitro-pyridinesulfenyl protecting group, widely utilized in peptide synthesis and biochemical research. This compound is valued for its role in the selective protection of thiol groups, enabling controlled disulfide bond formation and modification of cysteine residues in complex molecules. It is primarily sought by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in advanced peptide chemistry and proteomics.

Application

• Peptide Synthesis: Acts as a key reagent for the reversible protection of cysteine thiol groups during solid-phase and solution-phase peptide synthesis.
• Disulfide Bond Engineering: Facilitates the controlled formation and scrambling of disulfide bridges in synthetic peptides and proteins for structure-activity studies.
• Bioconjugation: Used to modify cysteine-containing proteins, antibodies, or other biomolecules for labeling, immobilization, or functionalization.
• Pharmaceutical Intermediate: Serves as a building block in the research and development of peptide-based therapeutics and diagnostic agents.
• Biochemical Research: Employed in studies of protein folding, enzyme mechanisms, and redox biology where specific cysteine modification is required.
• Protecting Group Chemistry: Provides a selectively removable protecting group in multi-step organic syntheses involving sensitive sulfur functionalities.

Basic Information

Product Name	S-(3-Nitro-2-Pyridinesulfenyl)Cysteine
CAS No.	79546-55-7
Molecular Formula	C8H9N3O4S2
Molecular Weight	275.30 g/mol
Synonyms	S-(3-Nitro-2-pyridylthio)cysteine; Cysteine, S-(3-nitro-2-pyridinylthio)-; 3-Nitro-2-pyridinesulfenyl cysteine; NPys-Cysteine; 2-Pyridinesulfenyl, 3-nitro-, S-ester with cysteine; (2R)-2-Amino-3-[(3-nitro-2-pyridyl)sulfanyl]propanoic acid; S-(3-Nitro-2-pyridylthio)-L-cysteine; L-Cysteine, S-(3-nitro-2-pyridinylthio)-
EINECS	Contact for details

Quality Control

Our S-(3-Nitro-2-Pyridinesulfenyl)Cysteine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.