Description

(1R,2R,3R,4S)-Bicyclo[2.2.1]Hept-5-Ene-2,3-Diyldimethanol is a high-purity, stereochemically defined chiral building block of significant synthetic utility. This compound matters for its rigid, functionalized norbornene skeleton, which is instrumental in constructing complex molecular architectures with precise spatial orientation. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in asymmetric synthesis, ligand development, and polymer chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Catalyst & Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Advanced Polymer Monomer: Serves as a functional monomer for creating specialty polymers with unique thermal or mechanical properties via ring-opening metathesis polymerization (ROMP).
• Agrochemical Synthesis: Employed in the research and production of chiral agrochemicals, such as herbicides and fungicides.
• Material Science Research: Utilized in the development of novel organic frameworks, dendrimers, and liquid crystalline materials.
• Cross-coupling Reactions: The diol functionality can be modified to create sophisticated coupling partners for metal-catalyzed reactions.

Basic Information

Product Name	(1R,2R,3R,4S)-Bicyclo[2.2.1]Hept-5-Ene-2,3-Diyldimethanol
CAS No.	79516-58-8
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	(1R,2R,3R,4S)-Bicyclo[2.2.1]hept-5-ene-2,3-dimethanol; (1R,2R,3R,4S)-5-Norbornene-2,3-dimethanol; endo,endo-5-Norbornene-2,3-dimethanol; (1R,2R,3R,4S)-2,3-Bis(hydroxymethyl)bicyclo[2.2.1]hept-5-ene; Chiral Norbornene Diol Derivative
EINECS	Contact for details

Quality Control

Our (1R,2R,3R,4S)-Bicyclo[2.2.1]Hept-5-Ene-2,3-Diyldimethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.