Description

(2S)-Dimethyl 8-Acetyl-3,3A,8,8A-Tetrahydropyrrolo[2,3-B]Indole-1,2(2H)-Dicarboxylate is a high-purity, chiral synthetic intermediate of significant importance in advanced organic synthesis. Its complex fused-ring indole structure makes it a versatile building block for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for neurological and oncological targets.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex alkaloids and other bioactive molecules for drug discovery and development.
• Organic Synthesis Building Block: Used in asymmetric synthesis and multi-step reactions to construct intricate polycyclic frameworks found in natural products.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the creation of novel compound libraries for high-throughput screening.
• Academic & R&D Laboratories: Serves as a specialized reagent for methodological studies in synthetic organic chemistry and catalysis.
• Precursor for Fine Chemicals: Can be further functionalized to produce high-value specialty chemicals for various advanced material applications.

Basic Information

Product Name	(2S)-Dimethyl 8-Acetyl-3,3A,8,8A-Tetrahydropyrrolo[2,3-B]Indole-1,2(2H)-Dicarboxylate
CAS No.	79465-85-3
Molecular Formula	C17H18N2O5
Molecular Weight	330.34 g/mol
Synonyms	Dimethyl (2S)-8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2-dicarboxylate; (S)-Dimethyl 8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2-dicarboxylate; 8-Acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester, (2S)-; (2S)-1,2-Dimethoxycarbonyl-8-acetyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indole; Chiral pyrroloindole diester; CAS 79465-85-3
EINECS	Contact for details

Quality Control

Our (2S)-Dimethyl 8-Acetyl-3,3A,8,8A-Tetrahydropyrrolo[2,3-B]Indole-1,2(2H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including chiral purity analysis (HPLC), identity confirmation (IR, NMR), and assay determination to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.