Description

Dimethyl-(2S, 3Ar, 8As)-8-Acetyl-1,2,3,3A,8A-Hexahydropyrrolo[2,3]Indol-1,2-Dicarboxylate is a sophisticated chiral indole derivative, a key synthetic intermediate in advanced organic synthesis. Its complex fused-ring structure and defined stereochemistry make it a critical building block for constructing biologically active molecules. This high-purity compound is essential for research and development teams in the pharmaceutical and agrochemical industries seeking to develop novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Serves as a core scaffold for developing new-generation pesticides and herbicides with specific modes of action.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective reactions to create enantiomerically pure compounds.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Academic Research: Employed in universities and research institutes for methodological development in heterocyclic and natural product synthesis.
• Fine Chemical Production: Acts as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	Dimethyl-(2S, 3Ar, 8As)-8-Acetyl-1,2,3,3A,8A-Hexahydropyrrolo[2,3]Indol-1,2-Dicarboxylate
CAS No.	79465-83-1
Molecular Formula	C17H20N2O5
Molecular Weight	332.35 g/mol
Synonyms	Dimethyl 8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3-b]indole-1,2-dicarboxylate; (2S,3aR,8aS)-Dimethyl 8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3-b]indole-1,2-dicarboxylate; 8-Acetylhexahydropyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester; Pyrrolo[2,3-b]indole-1,2-dicarboxylic acid, 8-acetyl-1,2,3,3a,8a-hexahydro-, dimethyl ester, (2S,3aR,8aS)-; CAS 79465-83-1
EINECS	Contact for details

Quality Control

Our production of Dimethyl-(2S, 3Ar, 8As)-8-Acetyl-1,2,3,3A,8A-Hexahydropyrrolo[2,3]Indol-1,2-Dicarboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.