Description

5-Bromo-4-Nitrothiophene-2-Carbaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring bromo and nitro substituents on a thiophene aldehyde core, makes it a versatile precursor for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its reactive halogen and nitro groups.
• Material Science Research: Serves as a precursor for synthesizing functionalized polymers, conductive materials, and organic electronic components.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Sonogashira couplings to create complex biaryl systems.
• Ligand and Catalyst Development: Useful for constructing novel chelating ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	5-Bromo-4-Nitrothiophene-2-Carbaldehyde
CAS No.	79456-86-3
Molecular Formula	C5H2BrNO3S
Molecular Weight	235.04 g/mol
Synonyms	5-Bromo-4-nitro-2-thiophenecarboxaldehyde; 4-Nitro-5-bromothiophene-2-carbaldehyde; 2-Formyl-5-bromo-4-nitrothiophene; 5-Bromo-4-nitrothiophene-2-carboxaldehyde; 79456-86-3; Thiophene-2-carboxaldehyde, 5-bromo-4-nitro-
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Nitrothiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Solubility	Soluble in common organic solvents (DMSO, DMF, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.