Description

1,5-Naphthyridine-4-Thiol is a specialized heterocyclic organic compound featuring a naphthyridine core with a thiol functional group. This unique structure makes it a valuable building block and intermediate in advanced chemical synthesis, particularly for applications requiring precise molecular architecture. It is primarily utilized by pharmaceutical research and agrochemical development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Serves as a chelating agent or ligand precursor in coordination chemistry and catalysis.
• Material Science: Incorporated into the development of organic semiconductors, conductive polymers, or metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or linker in bioconjugation and proteomics research.

Basic Information

Product Name	1,5-Naphthyridine-4-Thiol
CAS No.	79425-89-1
Molecular Formula	C8H6N2S
Molecular Weight	162.21 g/mol
Synonyms	4-Mercapto-1,5-naphthyridine; 1,5-Naphthyridine-4-thione; 4-Thiol-1,5-naphthyridine; 4-Sulfanyl-1,5-naphthyridine; 1,5-Naphthyridin-4-thiol; 4-Hydro-1,5-naphthyridine-4-thione; 1,5-Diazanaphthalene-4-thiol
EINECS	Contact for details

Quality Control

Our 1,5-Naphthyridine-4-Thiol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and should be handled with care to minimize exposure to air.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.