Description

Bicyclo[2.2.0]Hexane-1-Carboxylic Acid, Methyl Ester (9Ci) is a specialized bicyclic organic ester, a high-purity building block valued for its unique strained ring structure and functional group versatility. This compound is critical for advanced organic synthesis, particularly in pharmaceutical research and fine chemical development where its rigid framework is used to modulate molecular properties. It serves as a key intermediate for medicinal chemists and R&D scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and complex organic materials.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and complex metabolic pathways.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where its bicyclic structure contributes to biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers and high-performance resins with unique thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Diels-Alder reactions, ring-opening polymerizations, and other transformations that leverage its strained ring system.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex aroma chemicals with novel olfactory profiles due to its distinct molecular geometry.
• Ligand & Catalyst Development: Used to create novel chiral ligands and organocatalysts for asymmetric synthesis in fine chemical production.

Basic Information

Product Name	Bicyclo[2.2.0]Hexane-1-Carboxylic Acid, Methyl Ester (9Ci)
CAS No.	79368-51-7
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	Methyl bicyclo[2.2.0]hexane-1-carboxylate; 1-Bicyclo[2.2.0]hexanecarboxylic acid methyl ester; Methyl 1-bicyclo[2.2.0]hexanecarboxylate; Bicyclo[2.2.0]hexane-1-carboxylic acid methyl ester; NSC 338183; 1-Carbomethoxybicyclo[2.2.0]hexane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.0]Hexane-1-Carboxylic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our quality commitment supports compliance with cGMP guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.