Description

n-(tert-Butyldimethylsilyl)Phthalimide is a versatile organosilicon reagent widely used as a key intermediate in organic synthesis and pharmaceutical manufacturing. Its primary value lies in its role as a robust protecting group for amines, offering excellent stability under a wide range of reaction conditions. This compound is essential for researchers and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for complex molecule assembly. We supply this critical intermediate with a focus on consistent quality and reliable global availability.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected amine functionalities.
• Peptide Synthesis: Used as an amino-protecting reagent (N-silylation agent) in solid-phase and solution-phase peptide chemistry.
• Agrochemical Development: Serves as a key intermediate in the research and production of novel herbicides, fungicides, and insecticides.
• Organic Synthesis Reagent: Employed in multi-step synthetic routes for natural products, fine chemicals, and complex organic molecules requiring temporary amine protection.
• Material Science Research: Utilized in the development of specialty polymers and advanced materials where silyl-protected monomers are required.
• Academic & R&D Laboratories: A standard reagent for methodological development and exploratory chemistry in university and industrial research settings.

Basic Information

Product Name	n-(tert-Butyldimethylsilyl)Phthalimide
CAS No.	79293-84-8
Molecular Formula	C14H19NO2Si
Molecular Weight	261.40 g/mol
Synonyms	N-(tert-Butyldimethylsilyl)phthalimide; 2-[(tert-Butyldimethylsilyl)amino]isoindoline-1,3-dione; N-(tert-Butyldimethylsilyl)phthalimide; N-t-Butyldimethylsilylphthalimide; N-TBDMS-Phthalimide; Phthalimide, N-[(1,1-dimethylethyl)dimethylsilyl]-; N-(tert-Butyldimethylsilyl)-1H-isoindole-1,3(2H)-dione
EINECS	Contact for details

Quality Control

Our n-(tert-Butyldimethylsilyl)Phthalimide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and our quality commitment supports compliance in cGMP-related synthesis where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.