Description

Methyl 3-Isocyanatosulfonylthiophene-2-Carboxylate is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. Its unique structure, featuring both an isocyanate and a sulfonyl group on a thiophene core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its reactive isocyanate and electron-withdrawing sulfonyl group.
• Chemical Biology Probes: Utilized in the development of activity-based probes and labeling reagents for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Methyl 3-Isocyanatosulfonylthiophene-2-Carboxylate
CAS No.	79277-18-2
Molecular Formula	C7H5NO5S2
Molecular Weight	247.25 g/mol
Synonyms	Methyl 3-(isocyanatosulfonyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[(isocyanatosulfonyl)-, methyl ester; 3-Isocyanatosulfonylthiophene-2-carboxylic acid methyl ester; Methyl 3-isocyanatosulfonyl-2-thiophenecarboxylate; 3-(Isocyanatosulfonyl)thiophene-2-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Isocyanatosulfonylthiophene-2-Carboxylate is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.