Description

5-Trimethylsilylthiazole CAS NO 79265-36-4 is a specialized organosilicon-thiazole hybrid compound, serving as a versatile building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trimethylsilyl protecting group, which facilitates selective functionalization of the thiazole heterocycle. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thiazole-containing drug candidates, including potential antivirals, antibiotics, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the bioactivity of the thiazole moiety.
• Material Science Precursor: Acts as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed to synthesize novel N-heterocyclic ligands for transition metal catalysis and organocatalysis.
• Chemical Research Reagent: A valuable tool for academic and industrial R&D in heterocyclic and organosilicon chemistry for exploring new reaction pathways.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	5-Trimethylsilylthiazole
CAS No.	79265-36-4
Molecular Formula	C6H11NSSi
Molecular Weight	157.31 g/mol
Synonyms	5-(Trimethylsilyl)thiazole; Thiazole, 5-(trimethylsilyl)-; 5-TMS-thiazole; Trimethyl(2-thiazolyl)silane; 2-(Trimethylsilyl)thiazole; 5-(Trimethylsilyl)-1,3-thiazole; 5-Trimethylsilyl-thiazole
EINECS	Contact for details

Quality Control

Our 5-Trimethylsilylthiazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original sealed packaging to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.