Description

2,5-Bistrimethylsilanylthiazole CAS NO 79265-34-2 is a specialized organosilicon-protected thiazole derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile synthon, enabling the controlled introduction of the thiazole heterocycle under mild conditions. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel active ingredients, particularly in medicinal chemistry and materials science applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, especially those containing thiazole or modified thiazole moieties for antiviral, anticancer, or anti-inflammatory activity.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the thiazole ring contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: Acts as a stable, protected substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille) for constructing complex molecular architectures.
• Ligand and Catalyst Development: Employed in the preparation of novel nitrogen-sulfur containing ligands for transition metal catalysis.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in heterocyclic and organosilicon chemistry.

Basic Information

Item	Details
Product Name	2,5-Bistrimethylsilanylthiazole
CAS No.	79265-34-2
Molecular Formula	C9H19NS2Si2
Molecular Weight	249.55 g/mol
Synonyms	2,5-Bis(trimethylsilyl)thiazole; 2,5-Bis(trimethylsilyl)-1,3-thiazole; Thiazole, 2,5-bis(trimethylsilyl)-; 2,5-Bis-TMS-thiazole; 2,5-Di(trimethylsilyl)thiazole; 2,5-Bis(trimethylsilanyl)thiazole; 2,5-Bis(trimethylsilyl)thiazole (TMS-protected thiazole)
EINECS	Contact for details

Quality Control

Every batch of 2,5-Bistrimethylsilanylthiazole is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by GC or HPLC), identity confirmation, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.