Description

(3S)-2-Carbobenzoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, non-natural amino acid derivative and a key chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically defined, protected scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in peptidomimetic and protease inhibitor research.
• Peptide Chemistry: Serves as a protected, constrained amino acid analog for the solid-phase and solution-phase synthesis of modified peptides with enhanced stability or biological activity.
• Chemical Biology Research: Used as a tool compound or building block in the study of protein-protein interactions and enzyme mechanisms.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Ligand Development: Acts as a precursor for creating specialized ligands used in catalysis or molecular recognition.

Basic Information

Product Name	(3S)-2-Carbobenzoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	79261-58-8
Molecular Formula	C19H17NO4
Molecular Weight	323.34 g/mol
Synonyms	(3S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, 2-[(phenylmethoxy)carbonyl]-; (S)-2-((Benzyloxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (S)-2-Cbz-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (S)-2-Carbobenzoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; Cbz-Tic-OH; Z-Tic-OH; (S)-N-Cbz-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid; (3S)-2-[(Benzyloxy)carbonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our (3S)-2-Carbobenzoxy-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.